Separation and determination of Bisphenol A in water and food samples by MIL-101(Fe) as sorbent and multivariate optimization

Abstract

Bisphenol A (2,2-bis(4-hydroxyphenyl)propane), known as BPA, is a chemical compound that is widely used in industry as a monomer in the production of epoxy resins and as a coating on the inner surface of food and beverage cans [1]. BPA may directly enter the environment, food, and water. Therefore, from various aspects, including maintaining public health, protecting the environment, and controlling the quality of products, it is necessary to determine this pollutant in different environments [2]. In this research, MIL-101(Fe) as sorbent synthesized, characterized and used in the dispersive micro-solid phase extraction method (D-μ-SPE) for the preconcentration, separation and determination trace amount of BPA. The effective parameters on the extraction process including the pH, sorbent dose, adsorption time and temperature were optimized by central composite design (CCD) [3]. Under optimal conditions the linear range (LDR), detection limit (LOD) and the relative standard deviation (%RSD) for BPA were 30-1000 ng mL-1 , 9.1 ng mL-1 and 2.0% (n=3), respectively. Finally, the proposed method was successfully applied for the preconcentration and determination of BPA in water and food samples.