The Suzuki-Miyaura Reaction of Phenylboronic Acid with Different Aryl Halides Catalyzed with Cu (II) Salen Complex@KCC-1 as a Recyclable Heterogeneous Catalyst

Abstract

The carbon-carbon bond formation reactions have always been interesting for scientists because of their wide range of uses in organic chemistry. The Suzuki-Miyaura reaction is a famous reaction for the C-C bond formation. The Suzuki-Miyaura reaction is applied to synthesize a wide range of pharmaceutical and biological compounds. In this research, a Cu (II) Salen complex supported on KCC-1 (Cu (II) Salen complex@KCC-1) has been synthesized and characterized for the C-C bond formation reaction. The synthesized catalyst was determined to be an effective heterogeneous catalyst for the coupling reaction of Suzuki-Miyaura. The synthesized catalyst was characterized via XRD, FT-IR, TEM, and EDX, and the organic compound was identification with melting-point, FT-IR, and 1H NMR techniques. Cu (II) Salen @ KCC-1 complex can be separated and reused simply in the reaction mixture and reused several consecutive runs without significantly reducing the catalyst’s performance. To identify each product, FT-IR, 1H NMR, and melting point techniques were applied.