| Authors | حیدر رئیسی |
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| Journal | Journal of Molecular Liquids |
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| Page number | 125608-125620 |
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| Serial number | ۴۱۰ |
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| Volume number | ۲۴ |
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| IF | 3.648 |
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| Paper Type | Full Paper |
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| Published At | ۲۰۲۴ |
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| Journal Grade | ISI |
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| Journal Type | Typographic |
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| Journal Country | Netherlands |
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| Journal Index | JCR،Scopus |
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| Keywords | Human epidermal growth factor receptors, Molecular docking technique, Molecular dynamics simulation KW, Quantum mechanics calculations, Alkaloid and lead compounds KW, Molecular dynamics simulation |
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Abstract
Human Epidermal Growth Factor Receptor-2 (HER2), a transmembrane tyrosine kinase receptor, has been associated with several types of cancer, including breast, lung, ovarian, etc. Therefore, this receptor is targeted by a variety of therapeutic approaches for cancer treatments. The alkaloid and lead compounds are among the selective and potent HER2 inhibitors that have been reported so far.
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