| نویسندگان | حیدر رئیسی |
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| نشریه | Journal of Molecular Liquids |
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| شماره صفحات | 125608-125620 |
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| شماره سریال | ۴۱۰ |
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| شماره مجلد | ۲۴ |
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| ضریب تاثیر (IF) | 3.648 |
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| نوع مقاله | Full Paper |
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| تاریخ انتشار | ۲۰۲۴ |
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| رتبه نشریه | ISI |
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| نوع نشریه | چاپی |
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| کشور محل چاپ | هلند |
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| نمایه نشریه | JCR،Scopus |
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| کلید واژه ها | Human epidermal growth factor receptors, Molecular docking technique, Molecular dynamics simulation KW, Quantum mechanics calculations, Alkaloid and lead compounds KW, Molecular dynamics simulation |
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چکیده مقاله
Human Epidermal Growth Factor Receptor-2 (HER2), a transmembrane tyrosine kinase receptor, has been associated with several types of cancer, including breast, lung, ovarian, etc. Therefore, this receptor is targeted by a variety of therapeutic approaches for cancer treatments. The alkaloid and lead compounds are among the selective and potent HER2 inhibitors that have been reported so far.
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