Authors | _ |
---|---|
Journal | New Journal of Chemistry |
Page number | 500-514 |
Serial number | 47 |
Volume number | 1 |
IF | 3.269 |
Paper Type | Full Paper |
Published At | 2022 |
Journal Type | Typographic |
Journal Country | Iran, Islamic Republic Of |
Journal Index | JCR،Scopus |
Abstract
An ultrasensitive and disposable sensor based on modified screen-printed carbon electrode (SPCE) was developed for rapid quantification of rifampicin (RIF) and isoniazid (INZ) by differential pulse voltammetry (DPV) in complex media. The surface of SPCE was simply electrochemically modified with reduced graphene oxide and nickel hydroxide nanofilm (Ni(OH)2@rGO/SPCE) and characterized by atomic force microscopy, and cyclic voltammetry. Individual and simultaneous detections of RIF and INZ were accomplished using Ni(OH)2@rGO/SPCE in the ranges of 1.0*10-9 - 2.0*10-7 mol L-1 and 2.010-7 -5.010-5 mol L-1 for RIF and 5.010-8 - 1.010-6 mol L-1 and 1.010-6-1.010-4 mol L-1 for INZ with detection limits of 3.010-9 mol L-1 and 5.010-9 mol L-1, respectively. The developed sensor was successfully applied for the rapid simultaneous determination of analytes in real samples.
tags: Rifampicin; Isoniazid; Electrochemical sensing; Modified screen-printed carbon electrode; Reduced graphene oxide; Nickle hydroxide nanofilm