Magnetic dispersive micro solid phase extraction based on 2-aminothiophenol as nanoadsorbent for quantification of 2, 4-dinitrophenol

Abstract

Background: 2, 4-dinitro phenol (2, 4-DNP) one of the phenolic compounds is primarily used as a chemical intermediate for the production of azo dyes and wood preservatives. Due to their toxicity in the environment, have adverse effects on the environment and human health [1]. 2, 4-DNP can remain in the environment for a long time due to its stability and bioaccumulation. Methods: In this work, the 2-aminothiophenol as an organosulfur compound is synthesized and characterized by FT-IR, TEM, XRD and TGA techniques and used as nanosorbent in the magnetic dispersive micro solid phase extraction (MD-MSPE) method for the determination of 2,4-DNP [2]. In MD-MSPE method, the adsorbent is dispersed in sample solution by ultrasonic, and after completing the absorption of the analyte, the absorbent is separated by a magnet from the solution, and then the analyte solution is transferred to the UV-Vis spectrophotometry [3]. Results: To examine the most important parameters including amount of sorbent, pH of the solution, extraction time and desorption time on the MD-MSPE, a four factor central composite design (CCD) combined with response surface modeling (RSM) was accomplished [4, 5]. Under optimum conditions, LOD, LOQ and RSD of the method were found to be 5.4 ng mLି-1, 17.82 ng mL-1 ି and 7.18 %, respectively. Conclusion: The MD-MSPE method based on the 2-aminothiophenol as nanosorbent successfully applied to determination of target analyte in various water samples. Furthermore, this method offers significant advantages such as the simplicity of the extraction, speed, high selectivity and sensitivity.