La(OTf)2-amine grafted-GO as the first multifunctional catalyst for the one-pot three-component synthesis of α-aminophosphonates

Abstract

In this paper, the applicability of immobilized lanthanum(III) triflate on amine grafted graphene oxide [La(OTf)2-amine grafted-GO] as the first multifunctional catalyst is described for the efficient synthesis of α-aminophosphonates by the one-pot three-component reaction of carbonyl compounds, substituted anilines and trialkyl phosphites. Various α-aminophosphonates were synthesized in good to high yields under solvent-free conditions at room temperature. The catalyst was reused five times without significant loss of its activity