Comparison of motion control strategies during gait initiation of young women with multiple sclerosis in response to external disturbances

Abstract

Multiple Sclerosis is a chronic inflammatory disease of the immune system that affects the central nervous system and can lead togait changes and often imbalances. Postural imbalance and consequently change in walking are the main problem of MS patients,which limits their daily activities and increases the risk of falls. It is 2-3 times more prevalent in women than men and is usually .diagnosed between the ages of 20-50 The purpose of this study was to compare movement control strategies during gait initiation of young women aged 20-40 years withmultiple sclerosis in response to external perturbation with emphasis on selected spatio-temporal variables, lower extremity angularkinematics, and center of mass pressure changes. 10 MS patients and 10 healthy individuals participated in the study and The gaitinitiation protocol was performed from steady-state to steady-state gait and the information of right, left, knee and ankle joints wasevaluated with 8 motion analysis cameras and 2 force plates.After filtering and normalizing raw data, independent t-test betweentwo groups showed that MS patients had more Angular changes in the sagittal plane, reduced angular velocity of ankle swing footand lower hip angular changes in the frontal surface and decreased the ankle and knee rotation in stance foot (the foot that is at thestart movement as a contact foot) and the maximum distance to the center of pressure AP, as well as more changes in the center ofpressure of the center relative to the center of mass in AP and ML direction feedforward phase, and more changes in distance center .of pressure ratio The center of mass in feedback phase start their walking According to research findings, MS patients use hip strategies to maintain their balance and posture and control great movement.with off-stage ankle rotations