Effects of different exercise intensities on serum levels of Apelin and Chemerin in male Wistar rats

Abstract

Background: Adipose tissue is a large source of fat that has the task of storing fat in the body, and is also extremely important in energy homeostasis. The purpose of this study was to compare the effects of different exercise intensities (12 weeks) on serum levels of Apelin and Chemerin which are produced by adipose tissue in male Wistar rats. Method: In this study, 30 male Wistar rats randomly divided into three groups (n=10); 1. Control group, 2. High intensity group and 3. Low intensity group. Rats in exercise training groups ran on a treadmill with low and high intensity for 12 weeks (5 sessions per week). The serum levels of Aplin and Chemerin were measured using the ELISA technique, and the inter group comparison was done using one-way analysis of variance (One-Way ANOVA) with the Tukey test. Results: The findings suggest that both low and high intensity exercise training can increase the serum levels of Apelin (P<0.05); but there was no significant difference between the serum levels of Apelin in different exercise training groups. There were no significant changes in serum levels of Chemerin after two different exercise intensities. Conclusion: To summarize, the intensity of exercise training can be a criterion for Apelin secretion in adipose tissue, whereas Chemerin, according to our observations, is not a trainable factor.